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Denture stomatitis is a chronic inflammatory condition of the oral mucosa that
generally occurs in users of removable dentures. The cause is multifactorial
but is often associated with the presence of Candida albicans. The mucosa
which is covered by the denture base also reduces the function of saliva which
functions as a cleanser for the oral cavity and results in food waste
accumulating and microorganisms such as Candida albicans can increase in
number. Candida albicans is a normal flora of the oral cavity which is an
opportunistic pathogen. The starfruit plant (Averrhoa billimbi l) is a natural
ingredient that can be used as an antifungal agent. The aim was to determine
the ratio of the effectiveness of starfruit leaf extract (Averrhoa billimbi) between
the concentrations of 12.5%, 25%, 50%, 100%, control + (Clorhexidine) and
control - (Aquadest) in reducing the number of Candida albicans colonies. The
test method used the dilution method, the colony count of Candida albicans
using a spectrophotometer. The results of the one way ANOVA statistical test
resulted in a significance value of p = 0.000 (p <0.05) which means that there
is a difference in the average concentration of Candida albicans between the
extract concentrations of 12.5%, 25%, 50%, 100%, control + and control. -
namely 6.78 ± 0.35, 6.27 ± 0.21, 4.89 ± 0.29, 1.01 ± 0.18, 0.59 ± 0.19 and 9.13
± 2.28 in inhibiting growth Candida albicans and this was confirmed by the
Tukey HSD posthoc test. The conclusion of this study is that there is a
difference between the antifungal effectiveness of starfruit leaf extract
(Averrhoa billimbi) concentrations of 12.5%, 25%, 50% and 100% in inhibiting
the growth of Candida albicans colonies.


Candida albicans Averrhoa bilimbi L Clorhexidine

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How to Cite
Idamawati, M. Simanjuntak, R. N., Molek, & Listyaning Kartiko Kinasih. (2021). Activity of Averrhoa Bilimbi L Leaf Extract as Denture Cleaner Towards The Number of Colonies of Candida Albicans in Heat Cured Resin with a 30 Minutes Period. Biomedical Journal of Indonesia, 7(2), 402-407.