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The cell cycle is a vital process in the life of every organism. Normally, the cell cycle
results in cell division. Cell division consists of 2 main processes, namely DNA
replication and chromosome division that has been duplicated into 2 daughter cells.
Cyclin is expressed periodically so that the cyclin concentration varies at each phase of
the cell cycle. Cdks are threonine or serine protein kinases which must bind to cyclin
for its activation. The concentration of Cdks is relatively constant during the cell cycle.
Cyclin-dependent kinase inhibitor (CKI) is a protein that can inhibit Cdk activity by
binding to Cdk or the cyclin-Cdk complex


Cell cycle Cdk CKI Rb and p53 pathway

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How to Cite
Hayati, L., & Rachmat Hidayat. (2020). Regulation of Cell Cycle. Biomedical Journal of Indonesia, 6(3), 84-90.

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