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Abstract

Eosinophilic esophagitis is an immune-allergic pathology of multifactorial etiology (genetic and environmental) characterized by major symptoms of esophageal dysphagia and eosinophil-predominant inflammation of the esophageal mucosa that affects both pediatric and adult patients. EoE is an immune-mediated disease by which environmental and food antigens stimulate the Th2 inflammatory cascade. It is correlated with food allergy and atopy condition such as asthma, atopy dermatitis, rhinitis allergic and often in conjunction with Gastroesophageal Reflux Disease (GERD). Eosinophilic esophagitis (EoE) was first described in the 1990s, showing an increasing incidence and prevalence since then, in the United States is estimated to be approximately 57 per 100,000 persons being the leading cause of food impaction and the major cause of dysphagia. Its symptoms, which include heartburn, regurgitation, and esophageal stenosis. This symptomps similar to those of gastroesophageal reflux disease, causing delays in diagnosis and treatment. The endoscopic findings such as furrows, esophageal mucosa trachealization, and whitish exudates, this diagnosis should be confirmed histologically confirmed by biopsy on the presence of more than 15 eosinophils per high-power field and the exclusion of other causes of eosinophilia. Management includes medications, diet, and surgical dilatation.

Keywords

Eosinophilic Esophagitis Dysphagia Atopy

Article Details

How to Cite
Zuleika, P. (2021). Eosinophilic Esophagitis: Atopy Conditions of the Esophagus. Archives of The Medicine and Case Reports, 2(2), 146-157. https://doi.org/10.37275/amcr.v2i2.493